horse at fence
female vet

WHAT IT TAKES TO DIAGNOSE PPID

PPID may present through a collection of subtle clinical signs. To accurately diagnose, use a combination of the following:

  • Horse's history
  • Complete physical examination
  • Appropriate diagnostic evaluation
woman and horse

PPID DOESN'T DISCRIMINATE

PPID was once thought of as an old horse disease.

  • Current accepted PPID prevalence is 21% of horses over the age of 15.1
  • Although rare, horses as young as five years old have been diagnosed with PPID.
  • PPID affects male and female horses, and has been identified in most breeds of horses and ponies.
horse in stall

EARLIER THE DIAGNOSIS, THE BETTER

PPID is a chronic, degenerative disease. And while there are management options available, recognizing the clinical signs and early diagnosis is the first step leading to the proper management of a horse with PPID.

CLINICAL SIGNS OF PPID

We can ID PPID.

Clinical signs associated with PPID can vary widely between horses and may develop gradually over time. In some cases, signs may be mild, intermittent, or overlap with other conditions, making diagnosis based on clinical presentation alone challenging. Laboratory testing plays a key role in helping veterinarians assess PPID risk and support more confident diagnostic decisions.

Lethargic brown horse in stall
Change in attitude/lethargy

A change in personality and/or a lack of energy.

 

Woman riding a horse western style
Decreased performance
Clinical sign
Regional hypertrichosis

Decreased or delayed shedding in specific areas (regions) of the horse’s body.

Brown horse with white mane that has delayed hair coat shedding
Delayed hair coat shedding

Delayed shedding of the winter coat may occur in some areas, and the summer coat may look different in these same areas.

Brown horse back with topline muscle loss
Loss of topline muscle

A gradual loss in muscle mass.

Clinical sign
Abnormal sweating

Increased or decreased sweating may occur.

Horse graphic of mare that has a difficult time getting in foal and/or carrying to term.
Infertility

Reproductive cycles may be abnormal or absent, potentially leading to infertility.

Brown horse being examined for desmitis/tendonitis
Desmitis/tendonitis
Brown horses with regional adiposity
Regional adiposity

Fat deposits may appear along the crest of the neck and tail head.

Black horse with x-ray
Laminitis

Inflammation of the laminae of the foot and increased tenderness.

Horse leg with tendon/ligament laxity
Tendon/ligament laxity
horse with altered mentation
Altered mentation

Sluggishness or decreased activity.

English style horse rider on white horse with exercise intolerance
Exercise intolerance

Decreased ability in physical exercise.

Brown horse with generalized hypertrichosis
Generalized hypertrichosis

Excessive hair growth over all of the body.

Loss of seasonal hair coat shedding

Loss of seasonal shedding compared to herd mates or past years.

Brown and white horse with topline muscle atrophy
Topline muscle atrophy

Prominent withers, sunken shoulders and/or prominent spine.

Brown horse with rounded abdomen
Rounded abdomen

The horse's belly may have a "rounded" hay belly appearance.

Clinical sign
Abnormal sweating

Increased or decreased sweating may occur.

Horses with polyuria/polydipsia drinking water
Polyuria/polydipsia

Increased urination and/or thirst.

Horse hoof with recurrent infection
Recurrent infections

A few examples are recurring secondary skin infections, hoof abscesses, conjunctivitis and sinusitis.

Veterinarian examining horses eye for recurrent corneal ulcers
Recurrent corneal ulcers
Horse graphic of mare that has a difficult time getting in foal and/or carrying to term.
Infertility

Reproductive cycles may be abnormal or absent, potentially leading to infertility.

Increased mammary gland secretions
Increased mammary gland secretions
Horse leg with tendon/ligament laxity
Tendon and suspensory ligament laxity

Tendon laxity may be observed where the fetlock "drops" toward the ground when bearing weight.

Black horse with x-ray
Laminitis

Inflammation of the laminae of the foot and increased tenderness.

Brown horses with regional adiposity
Regional adiposity

Fat deposits may appear along the crest of the neck, the tail head and above the eyes.

LABORATORY CONFIRMATION

Identified a horse with potential PPID? Now it's time to test and confirm. 

It is easy to take part in our IDPPID Testing Program. Just enroll a horse that has clinical signs associated with PPID by:

  1. Filling out a form
  2. Then submitting plasma samples

Typically, it takes approximately 3 to 5 working days after the sample arrives at Cornell University Animal Health Diagnostic Center (AHDC) to receive final results.

Want more resources?

Visit our resource library to gain information on PPID, EMS, testing and more.

REFERENCE